GLOSSARY OF TERMS

E

E-mail (electronic mail)
Allows users on the Internet and other networks (both local and global) to communicate electronically by sending messages to individuals, or groups of individuals. E-mail is, for most people, cheaper and faster than other communication channels such as fax and standard mail.

Economic analysis (synonym: economic evaluation)
Comparison of the costs and outcomes of alternative health care interventions. See cost-benefit analysis, cost-effectiveness analysis and cost-utility analysis.

Effect size

  1. A generic term for the estimate of effect for a study.
  2. A dimensionless measure of effect that is typically used for continuous data when different scales (e.g. for measuring pain) are used to measure an outcome and is usually  defined as the difference in means between the intervention and control groups divided by  the standard deviation of the control or both groups. See standardized mean difference.

Effectiveness
The extent to which a specific intervention, when used under ordinary circumstances, does  what it is intended to do. Clinical trials that assess effectiveness are sometimes called  management trials. See also intention-to-treat.

Efficacy
The extent to which an intervention produces a beneficial result under ideal conditions.  Clinical trials that assess efficacy are sometimes called explanatory trials and are  restricted to participants who fully co-operate.

EMBASE (Excerpta Medica database)
A European-based electronic database of pharmacological and biomedical literature covering 3,500 journals from 110 countries. Years of coverage: 1974 to present.

Empirical
Empirical results are based on experience (or observation) rather than on reasoning alone.

Epidemiology
The study of the distribution and determinants of health-related states or events in specified populations.

Estimate of effect (synonym:  treatment effect)
In studies of the effects of healthcare, the observed relationship between an intervention  and an outcome expressed as, for example, a number needed to treat,
odds ratio, risk difference, relative risk, standardized mean difference, or weighted mean difference.

Event rate
The proportion of participants in a group in whom an event is observed. Thus, if out of  100 patients the event (e.g. a stroke) is observed in 32, the event rate is 0.32.

Evidence-based healthcare
The conscientious use of current best evidence in making decisions about the care of  individual patients or the delivery of health services.

External peer reviewer
A person with relevant content, methodological or user expertise who critically examines  reviews in her/his area of expertise.

External validity (synonyms: external  validity, generalisability, relevance, transferability)
The degree to which the results of an observation hold true in other settings. See also
validity.

Extramural
Outside (the walls or boundaries of) a place or institution. Refers to "external" sources of support (such as funding) as opposed to  "internal" (intramural) support.

Module managing team:
Prof Jimmy Volmink
E-mail: jvolmink@
cormack.uct.ac.za;

Last updated:
09-Feb-2006

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