where
to get help for alzheimer's disease?
How
is Alzheimer’s Disease Treated?
Alzheimer’s Disease (AD) is a slow disease, starting with mild memory problems and
ending with severe brain damage. The course the disease takes
and how fast changes occur vary from person to person. On average,
AD patients live from 8 to 10 years after they are diagnosed,
though the disease can last for as many as 20 years.
No treatment
can stop AD. However, for some people in the early and middle
stages of the disease, the drugs donepezil (Aricept®), rivastigmine
(Exelon®), or galantamine (Reminyl®) may help prevent
some symptoms from becoming worse for a limited time. Also,
some medicines may help control behavioural symptoms of AD such
as sleeplessness, agitation, wandering, anxiety, and depression.
Treating these symptoms often makes patients more comfortable
and makes their care easier for caregivers.
Developing
new treatments for AD is an active area of research. Scientists
are testing a number of drugs to see if they prevent AD, slow
the disease, or help reduce behavioural symptoms.
Research
has shown that vitamin E slows the progress of some consequences
of AD. Scientists now are studying vitamin E to learn whether
it can prevent or delay AD in patients with MCI.
Scientists
are testing two different types of nonsteroidal anti-inflammatory
drugs (NSAIDs) to find out if they slow the disease. There is
evidence that inflammation in the brain may contribute to AD
damage. Scientists believe that anti-inflammatory drugs such
as NSAIDs might help slow the progression of AD.
Recent research
suggests that ginkgo biloba, an extract made from the leaves
of the ginkgo tree, may be of some help in treating AD symptoms.
There is no evidence that ginkgo will cure or prevent AD. Scientists
now are trying to find out whether ginkgo biloba can delay or
prevent dementia in older people.
Research
is also under way to see if oestrogen reduces the risk of AD
or slows the disease. One study showed that oestrogen does not
slow the progression of already diagnosed disease, but more
research is needed to find out if it may play another role.
For example, scientists now are trying to find out whether oestrogen
can prevent AD in women with a family history of the disease.
People with
AD and those with Mild Cognitive Impairment (MCI) who want to help scientists test possible
treatments may be able to take part in clinical trials. Clinical
trials are studies to find out whether a new treatment is both
safe and effective. Healthy people also can help scientists
learn more about the brain and AD. To find out more about these
studies, contact the Mental Health Information Centre for a
clinical drug trial unit closest to you, tel. (021) 938 9229.
Is
There Help for Caregivers?
Most often, spouses or other family members provide the day-to-day
care for people with AD. As the disease gets worse, people often
need more and more care. This can be hard for caregivers and
can affect their physical and mental health, family life, job,
and finances.
The Alzheimer's
South Africa- Facing the Challenge of Dementia has branches across
the country that provide education and support for caregivers
and family members of people with AD. For more information,
contact the national office of ARDA for a branch closest to
you, tel. (011) 478-2234/5/6.
Information
obtained from own sources and http://www.alz.org
by:
Dr. Frans J. Hugo & Dr. Linda van Wyk
Panorama Memory Clinic
Psychiatry Clinic for Older Adults
139 Panorama Medical Centre
Hennie Winterbach Avenue
Panorama, 7500 South Africa
The Memory Line: 021 930 2177
Fax 021 930 2178
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